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swoosh The unique formula of Berocca
 

Berocca is a unique combination of vitamins and nutrients which is clinically proven to support mental performance and physical wellbeing. Compared with most other multivitamins, Berocca offers all B vitamins and vitamin C (the so called water-soluble vitamins) in a specific dosage together with the minerals calcium, magnesium and zinc. All these micro-nutrients are essential for brain and nerve functions and work in synergy for sustained mental performance.

Each tablet (effervescent and film coated) contains:

  Nutrient Chart
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swoosh Who needs Berocca
 

Berocca is recommended to all individuals carrying a risk of not getting enough vitamins and minerals from their diet.

Micronutrient deficiencies and cognitive performance:
The water soluble B vitamins, vitamin C and the mineral micronutrients magnesium and zinc are stored in the body only to a limited extent and upon any reduction of intake, impairment of absorption or increase in requirements, the body status begins to fall and may start to become deficient. The prolonged inadequate intake of all or any of the micronutrients in Berocca can have direct physiological effects on body and brain function and therefore on performance (as noted in Table 1 below).

Table 1. Consequences of water-soluble vitamin deficiencies on cognitive performance

(Rosenthal and Goodwin 1985; Rosenberg and Miller 1992; Institute of Medicine, 1998, 2000)

 
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Vitamin B1 Fatigue, mental changes (e.g. apathy, decrease in short-term memory, confusion and irritability)
Vitamin B2 B2 deficiency is most often accompanied by other micronutrient deficiencies. Severe B2 deficiency may impair the metabolism of vitamin B6 and the conversion of tryptophan to niacin
Vitamin B6 Depressed mood and neurological disturbances
Vitamin B12 Fatigue and weakness, irritability, depressed mood, loss of concentration to memory loss, mental confusion, disorientation
Folic acid Depression, insomnia, forgetfulness and difficulty in concentrating, irritability, apathy, fatigue and anxiety
Biotin Irritability, depressed mood, central nervous system abnormalities
Nicotinamide Marginal deficiency: Irritability, weakness, mental confusion and dizziness
Panthotenic acid Irritability and restlessness, fatigue, apathy and malaise, neurobiological symptoms such as numbness, muscle cramps. Myelin degeneration
Vitamin C Weakness, fatigue, depression
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swoosh Safety
 

With the recommended dosage of one tablet per day, Berocca has an exceptionally high safety profile. All Berocca ingredients are at levels well below the so called Upper Safety Levels, which have been officially established for vitamins and minerals by internationally accepted institutions like the US Institute of Medicine or the European Scientific Committee. In addition and compared with most other multivitamins, Berocca offers water-soluble vitamins only, of which any surplus will not be retained in the body.

Like for all other multivitamins allergic reactions can not be completely excluded. For further information, please refer to the patient information leaflet.

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swoosh Clinical Trial
 

Carroll study (Psychopharmacology (2000) 150: 220-225):

This double blind placebo-controlled trial shows that the intake of Berocca can improve mental performance relative to placebo by lowering anxiety and perceived stress, improving concentration and reducing tiredness.

  Final Chart
  Conclusion
These findings demonstrate that Berocca significantly reduces anxiety and perceived stress.